Global Downstream Processing Market: Overview
Downstream processing is a process wherein purification is done and the biosynthetic products are recovered especially the pharmaceuticals that are obtained from the natural sources. The downstream processing includes five stages that are solid-liquid separation, intracellular products are released, concentration, chromatography method is used for purification and formulation. Solid-liquid separation method involves methods such as centrifugation, flocculation, flotation, and filtration.
Global Downstream Processing Market: Segmentation
The downstream processing market is globally segmented into technique, product, application, and end-user. On the basis of technique, the global market is segregated into solid-liquid separation, purification, and clarification/concentration. Based on the product, the market is categorized into filters, single-use products, chromatography columns and resins, membrane adsorbers, consumables, and accessories. Depending on the application, the market is divided into monoclonal antibody production, insulin production, erythropoietin production, fusion proteins, blood coagulation factors, medical enzymes, colony stimulating factors, interferons, growth hormones, anticoagulants, anti-bacterial, vaccine production, and immunoglobulin production. Based on the end user, the market is fragmented into contract manufacturing organizations (CMOS) and biopharmaceutical manufacturers.
Global Downstream Processing Market: Growth Factors
The major factor that contributes to the growth of the downstream processing market is the rising demand for the biopharmaceutical products. This is owing to the fact that downstream processing plays an important role in providing biopharmaceutical products that are completely pure and of high quality. Moreover, the increasing investments that are being made on the research and the development of the biopharmaceuticals drive the demand of the market. On the other hand, patent expiration of the popular biopharmaceuticals expects to open up new lucrative opportunities that will contribute to the growth of the market. Emerging markets of regions such as Asia-Pacific are likely to provide new market opportunities that will drive the growth of the downstream processing market. However, there are certain factors that are hampering the market growth which includes lack of skilled and experienced people and the high economy that is involved in installing the instruments. In addition, lack of single-use options and purification bottlenecks are challenging the market growth.
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Global Downstream Processing Market: Regional Analysis
The downstream processing market is geographically segmented into Asia-Pacific, North America, Europe, and Rest of the World. The region that is dominating the downstream processing market is North America and will still retain its position in the coming years. The key factor that contributes to this dominance is it is the leading region for the biopharmaceutical research and has a major market for the pharmaceuticals worldwide. Asia Pacific is anticipated to be the fastest growing market. The factors that attribute to this growth are the developing R&D infrastructure, substantial investments made by the market players, emerging academic excellence, and increasing government support are fuelling the growth of the market in the Asia Pacific region.
Global Downstream Processing Market: Competitive Players
Some of the key market players that are involved in the downstream processing market include Thermo Fisher Scientific Inc., Danaher Corporation, Merck Millipore, Sartorius Stadium Biotech S.A., and GE Healthcare.